Joseph Wu, PhD

Professor Emeritus, Psychiatry

Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. 2022 05 12; 185(10):1676-1693.e23. Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, Liu C, Sayed N, Shie JJ, Yeh CF, Yang KC, Lau E, Lynch KL, Rivas M, Kobilka BK, Wu JC. PMID: 35489334.
Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes. Stem Cell Reports. 2021 09 14; 16(9):2169-2181. Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, Childers MK, Denning C, Day JW, Wu JC, Pruitt BL, Blau HM. PMID: 34019816.
The impact of sleep deprivation on sexual behaviors and FAAH expression in the prefrontal cortex of male rats. Neurosci Lett. 2020 09 14; 735:135254. Amini M, Saboory E, Derafshpour L, Fakhari A, Wu JC, Bruggeman R, Asgharzadeh F, Ahmadalipour A. PMID: 32682844.
The chronotherapeutic treatment of bipolar disorders: A systematic review and practice recommendations from the ISBD task force on chronotherapy and chronobiology. Bipolar Disord. 2019 12; 21(8):741-773. Gottlieb JF, Benedetti F, Geoffroy PA, Henriksen TEG, Lam RW, Murray G, Phelps J, Sit D, Swartz HA, Crowe M, Etain B, Frank E, Goel N, Haarman BCM, Inder M, Kallestad H, Jae Kim S, Martiny K, Meesters Y, Porter R, Riemersma-van der Lek RF, Ritter PS, Schulte PFJ, Scott J, Wu JC, Yu X, Chen S. PMID: 31609530.
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. Stem Cell Reports. 2019 12 10; 13(6):960-969. Wnorowski A, Sharma A, Chen H, Wu H, Shao NY, Sayed N, Liu C, Countryman S, Stodieck LS, Rubins KH, Wu SM, Lee PHU, Wu JC. PMID: 31708475.
Usage of Therapeutic Sleep Deprivation: A Survey in Psychiatric Hospitals in Austria, Germany, and Switzerland. Behav Sleep Med. 2019 Nov-Dec; 17(6):713-720. Winkler D, Spies M, Al-Resheg Y, Wu JC, Bunney WE, Bunney BG, Kasper S, Pjrek E. PMID: 29775085.
Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas. Stem Cells. 2017 08; 35(8):1994-2000. Lee AS, Tang C, Hong WX, Park S, Bazalova-Carter M, Nelson G, Sanchez-Freire V, Bakerman I, Zhang W, Neofytou E, Connolly AJ, Chan CK, Graves EE, Weissman IL, Nguyen PK, Wu JC. PMID: 28600830.
Efficacy of CD34+ Stem Cell Therapy in Nonischemic Dilated Cardiomyopathy Is Absent in Patients With Diabetes but Preserved in Patients With Insulin Resistance. Stem Cells Transl Med. 2016 May; 5(5):632-8. Vrtovec B, Sever M, Jensterle M, Poglajen G, Janez A, Kravos N, Zemljic G, Cukjati M, Cernelc P, Haddad F, Wu JC, Jorde UP. PMID: 27025690.
Effects of transendocardial CD34+ cell transplantation in patients with ischemic cardiomyopathy. Circ Cardiovasc Interv. 2014 Aug; 7(4):552-9. Poglajen G, Sever M, Cukjati M, Cernelc P, Knezevic I, Zemljic G, Haddad F, Wu JC, Vrtovec B. PMID: 25097199.
Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. Nat Med. 2013 Aug; 19(8):998-1004. Lee AS, Tang C, Rao MS, Weissman IL, Wu JC. PMID: 23921754.
Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters? J Clin Psychopharmacol. 2012 Feb; 32(1):110-3. Reist C, Wu JC, Lilja Y, Mukherjee J, Gripeos D, Constantinescu C, Raggi MA, Mercolini L, Ozdemir V. PMID: 22198458.
Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in ?4 carriers. Alzheimers Dement. 2012 Jul; 8(4):352-6. Deeny SP, Winchester J, Nichol K, Roth SM, Wu JC, Dick M, Cotman CW. PMID: 22226798.
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol. 2011 Aug 14; 29(9):829-34. Tang C, Lee AS, Volkmer JP, Sahoo D, Nag D, Mosley AR, Inlay MA, Ardehali R, Chavez SL, Pera RR, Behr B, Wu JC, Weissman IL, Drukker M. PMID: 21841799.
Reversing brain damage in former NFL players: implications for traumatic brain injury and substance abuse rehabilitation. J Psychoactive Drugs. 2011 Jan-Mar; 43(1):1-5. Amen DG, Wu JC, Taylor D, Willeumier K. PMID: 21615001.
Inducible expression of stem cell associated intermediate filament nestin reveals an important role in glioblastoma carcinogenesis. Int J Cancer. 2011 Jan 15; 128(2):343-51. Lu WJ, Lan F, He Q, Lee A, Tang CZ, Dong L, Lan B, Ma X, Wu JC, Shen L. PMID: 20669222.
CRY2 is associated with depression. PLoS One. 2010 Feb 24; 5(2):e9407. Lavebratt C, Sjöholm LK, Soronen P, Paunio T, Vawter MP, Bunney WE, Adolfsson R, Forsell Y, Wu JC, Kelsoe JR, Partonen T, Schalling M. PMID: 20195522.
Effects of cell number on teratoma formation by human embryonic stem cells. Cell Cycle. 2009 Aug 15; 8(16):2608-12. Lee AS, Tang C, Cao F, Xie X, van der Bogt K, Hwang A, Connolly AJ, Robbins RC, Wu JC. PMID: 19597339.
Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder. Biol Psychiatry. 2009 Aug 01; 66(3):298-301. Wu JC, Kelsoe JR, Schachat C, Bunney BG, DeModena A, Golshan S, Gillin JC, Potkin SG, Bunney WE. PMID: 19358978.
Sleep deprivation PET correlations of Hamilton symptom improvement ratings with changes in relative glucose metabolism in patients with depression. J Affect Disord. 2008 Apr; 107(1-3):181-6. Wu JC, Gillin JC, Buchsbaum MS, Schachat C, Darnall LA, Keator DB, Fallon JH, Bunney WE. PMID: 18031825.
Frontal lobe metabolic decreases with sleep deprivation not totally reversed by recovery sleep. Neuropsychopharmacology. 2006 Dec; 31(12):2783-92. Wu JC, Gillin JC, Buchsbaum MS, Chen P, Keator DB, Khosla Wu N, Darnall LA, Fallon JH, Bunney WE. PMID: 16880772.
Molecular imaging of cardiac stem cell transplantation. Curr Cardiol Rep. 2006 Mar; 8(2):147-54. Sheikh AY, Wu JC. PMID: 16524542.
Human gene therapy and imaging: cardiology. Eur J Nucl Med Mol Imaging. 2005 Dec; 32 Suppl 2:S346-57. Wu JC, Yla-Herttuala S. PMID: 16096829.
Brightening depression. Science. 2004 Jan 23; 303(5657):467-9. Wirz-Justice A, Terman M, Oren DA, Goodwin FK, Kripke DF, Whybrow PC, Wisner KL, Wu JC, Lam RW, Berger M, Danilenko KV, Kasper S, Smeraldi E, Takahashi K, Thompson C, van den Hoofdakker RH. PMID: 14739440.
A PET study of the pathophysiology of negative symptoms in schizophrenia. Positron emission tomography. Am J Psychiatry. 2002 Feb; 159(2):227-37. Potkin SG, Alva G, Fleming K, Anand R, Keator D, Carreon D, Doo M, Jin Y, Wu JC, Fallon JH. PMID: 11823264.
Clinical neurochemical implications of sleep deprivation's effects on the anterior cingulate of depressed responders. Neuropsychopharmacology. 2001 Nov; 25(5 Suppl):S74-8. Wu JC, Buchsbaum M, Bunney WE. PMID: 11682278.
Prediction of antidepressant effects of sleep deprivation by metabolic rates in the ventral anterior cingulate and medial prefrontal cortex. Am J Psychiatry. 1999 Aug; 156(8):1149-58. Wu J, Buchsbaum MS, Gillin JC, Tang C, Cadwell S, Wiegand M, Najafi A, Klein E, Hazen K, Bunney WE, Fallon JH, Keator D. PMID: 10450253.