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Oct 04, 2024 | UCI News
UC Irvine researchers are first to reveal role of ophthalmic acid in motor function control
A research team from the University of California, Irvine is the first to reveal that a molecule in the brain — ophthalmic acid — unexpectedly acts like a neurotransmitter similar to dopamine in regulating motor function, offering a new therapeutic target for Parkinson’s and other movement diseases.
Oct 03, 2024 | UCI News
UC Irvine receives initial $33 million in federal support for vaccine research
Philip Felgner, PhD, professor in residence in the Department of Physiology & Biophysics, and director of UC Irvine’s Adeline Yen Mah Vaccine Center, will lead a multi-institutional pandemic planning effort with this $33 million grant from the National Institute of Allergy and Infectious Diseases.
Sep 27, 2024 | UCI News
Circadian disruption, gut microbiome changes linked to colorectal cancer progression
Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body’s internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function.
Sep 05, 2024 | UCI News
UC Irvine, USC scientists begin research effort for damaged brain region treatments
With newly awarded funding from the National Science Foundation, researchers at UC Irvine and the Keck School of Medicine of USC will seek to revolutionize the treatment of neurological diseases through intelligent biocomputing.
Aug 21, 2024 | UCI News
UC Irvine discovery of ‘item memory’ brain cells offers new Alzheimer’s treatment target
Researchers from the University of California, Irvine have discovered the neurons responsible for “item memory,” deepening our understanding of how the brain stores and retrieves the details of “what” happened and offering a new target for treating Alzheimer’s disease.
Aug 20, 2024 | UCI News
UC Irvine-led team finds that compound in rosemary extract can reduce cocaine sensitivity
A team of researchers led by the University of California, Irvine has discovered that an antioxidant found in rosemary extract can reduce volitional intakes of cocaine by moderating the brain’s reward response, offering a new therapeutic target for treating addiction.
Aug 06, 2024 | UCI News
UC Irvine-led team reveals how TREM2 genetic mutation affects late-onset Alzheimer’s
Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset Alzheimer’s disease. Their first-of-their-kind insights into brain effects could yield new targets for early intervention.
Jul 31, 2024 | UCI News
UC Irvine Institute for Clinical & Translational Science receives $28 million NIH grant
The Institute for Clinical & Translational Science at the University of California, Irvine has been awarded more than $28 million over seven years from the National Institutes of Health as part of its Clinical & Translational Science Awards Program.
Jul 29, 2024 | UCI School of Medicine
UC Irvine Researchers identify key enzyme contributing to cancer health disparities in Latin American population
Researchers from the UC Irvine School of Medicine’s Pannunzio Lab have discovered that an enzyme expressed in B cells is a significant factor driving cancer health disparities within the Latin American population.
Jul 22, 2024 | UCI News
UC Irvine to establish All of Us research consortium in Southern California
A University of California, Irvine researcher is the principal investigator for a 5-year research award from the National Institutes of Health to lead a Southern California-based consortium for the nationwide All of Us Research Program. This funding will support the SoCal consortium in transforming the future of precision health research.