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Center for Epigenetics and Metabolism International 2022 Symposium

And Tribute to Paolo Sassone-Corsi
Arnold & Mabel Beckman Center of the National Academies of Sciences and Engineering 100 Academy Drive, Irvine, CA
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Headshot of Paolo Sassone-Corsi

2022 Center for Epigenetics and Metabolism International Symposium and Tribute to Paolo Sassone-Corsi

The Center for Epigenetics and Metabolism (CEM) is pleased to host its biennial international symposium, "Metabolic Medicine: Decoding Cellular Plasticity” on July 13-14, 2022. This event is a part of a series of symposia on epigenetics and chromatin research aimed at bringing together the scientific community in the field. This year, with the support of the UCI School of Medicine and Department of Biological Chemistry, we are pleased to offer complimentary registration as we return post-COVID and pay tribute to the late Paolo Sassone-Corsi. Space is limited – register now to reserve your space by clicking the registration button. 

Organizers: This meeting is hosted by the UCI School of Medicine and the Center for Epigenetics and Metabolism.

Watch the Livestream

2022 Center for Epigenetics and Metabolism International Symposium (Day 1)

Courtesy of UCI Media on Vimeo

2022 Center for Epigenetics and Metabolism International Symposium (Day 2)

Courtesy of UCI Media on Vimeo


    Wednesday, July 13, 2022

    Arnold & Mabel Beckman Center of the National Academy of Science & Engineering

  • 8:00 – 9:00 a.m.    
    Atrium: coffee, tea, and water

    9:00 – 9:30 a.m.     
    Opening and Introduction to the Symposium

    Michael J. Stamos, MD, Dean, UCI School of Medicine
    Ralph V. Clayman, MD, Distinguished Professor of Urology/Dean - UCI School of Medicine
    Thomas C. Cesario, MD, Dean - Emeritus, UCI School of Medicine
    Peter Kaiser, PhD, Chair, Department of Biological Chemistry, UCI School of Medicine

  • SESSION I   Transcription

    Chair: Richard Heyman, PhD, ORIC Pharma

    9:30 10:00 a.m.                
    Bob Roeder, PhD, The Rockefeller University, Transcriptional Regulatory Mechanisms 
    in Hematopoietic Malignancies

    10:00 10:30 a.m.              
    Ronald M. Evans, PhD, Salk Institute for Biological Studies, Physiology and its 
    Transcriptional Underpinning

    10:30 11:00 a.m.              
    Break coffee, tea, and water

    11:00 11:30 a.m.              
    Juan Carlos Izpisua Belmonte, PhD, Altos Labs, Biological Studies, Programming 
    Cell Rejuvenation

    11:30 a.m. – 12:00 p.m.
    Masao Doi, PhD, Kyoto University, Time as Medicine - Impact of Rejuvenating Circadian Transcriptional and Metabolic Activity

    12:00 2:00 p.m.               
    Lunch, Dining Room

  • SESSION II    Epigenetics

    Chair: Marcelo Wood, PhD, UCI

    2:00 – 2:30 p.m.    
    Asifa Akhtar, PhD, Max Planck Institute of Immunobiology and Epigenetics, MOF Complexes: Epigenetics Meets Metabolism

    2:30 – 3:00 p.m.    Bing Ren, PhD, UC San Diego, Ludwig Institute for Cancer Research, Epigenome Analysis in Health and Disease

    3:00 – 3:30 p.m.    
    Break – coffee, tea, and water

    3:30 – 4:00 p.m.    
    Juleen R. Zierath, PhD, Karolinska Institutet, Sweden/University of Copenhagen, Denmark, Epigenetic Control and the Circadian Clock: Turning Back Time on Diabetes Pathogenesis

    4:00 – 4:30 p.m.    
    Sarah Kimmins, PhD, McGill University, Environmental Programming of the Heritable Sperm Epigenome

    4:30 – 5:00 p.m.    
    Estée Lauder’s Tribute to Paolo Sassone-Corsi’s Legacy: Nadine Pernodet, PhD, Senior Vice President of Bioscience, Global R&D, Estée Lauder Companies

    5:00 – 7:00 p.m.    
    Cocktail Reception, Terrace Lawn


    Thursday, July 14, 2022



  • 9:00 9:30 a.m.                
    Registration - Atrium: coffee, tea, and water

    SESSION III    Circadian Rhythms

    Chair: Eric J. Stanbridge, PhD, UCI School of Medicine

    9:30 10:00 a.m.           
    Michael W. Young, PhD, The Rockefeller University, What Happens to Lonely Fly?

    10:00 10:30 a.m.        
    Break - 
    Coffee, tea, and water

    10:30 11:00 a.m.         
    Mitchell A. Lazar, MD, PhD, University of Pennsylvania Perelman School 
    of Medicine, Repression, Reverberations, and Reflections

    11:00 11:30 a.m.         
    Selma Masri, PhD, UCI, Mechanistic Insights Underlying Clock Disruption 
    in Colorectal Cancer

    11:30 1:30 p.m.          
    Lunch, Dining Room


  • SESSION IV   Metabolism

    Chair: Giuseppe Servillo, MD, PhD, University    ugia Italy

    1:30 – 2:00 p.m.    
    Johan Auwerx, MD, Ph.D., École Polytechnique Fédérale de Lausanne, Ceramide De Novo Synthesis Links Muscle    with Mitochondrial and Protein Homeostasis

    2:00 – 2:30 p.m.    
    Eric Verdin, MD, Buck Institute for Research on Aging, The Biology of Reversible Protein Acylation

    2:30 – 3:00 p.m.    
    Break - Coffee, tea, and water

    3:00 – 3:30 p.m.    
    Manuela Raffatellu, MD,    San Diego, New Insights on Mucosal Immunity to Commensal and Pathogenic Bacteria

    3:30 – 4:00    
    Eckel-Mahan,    MD Anderson/UTHealth, Circadian Rhythms Disease:        Journey Inspired    Sassone-Corsi

    4:00 p.m.    
    Closing Remarks


Scientific Organizers

Emiliana Borrelli, PhD
Emiliana Borrelli, PhD
  • Chancellor’s Professor, Department of Microbiology & Molecular Genetics, UCI School of Medicine

Richard Heyman, PhD
Richard Heyman, PhD
  • Chairman and Co-founder ORIC Pharma

Ronald M. Evans, PhD
Ronald M. Evans, PhD
  • Professor and Head of Gene Expression Laboratory
  • March of Dimes Chair in Molecular and Developmental Biology
  • Salk Institute for Biological Studies

Arnold & Mabel Beckman Center of the National Academies of Science & Engineering 100 Academy Drive
Irvine, CA 92617

Parking is complimentary.