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Feb 03, 2023 | PLOS One
Real-world performance of SARS-Cov-2 serology tests in the United States, 2020
Real-world performance of COVID-19 diagnostic tests under Emergency Use Authorization (EUA) must be assessed. We describe overall trends in the performance of serology tests in the context of real-world implementation.
Feb 01, 2023 | Microbiology Spectrum
Beyond Costs: Pragmatic Considerations for Pooling of SARS-CoV-2 Test Samples for Nursing Home Surveillance
Pooling of samples can increase throughput and reduce costs for large-scale SARS-CoV-2 testing when incidence is low. In a cross-sectional study of serial SARS-CoV-2 sampling of staff and residents at three nursing homes, laboratory labor constraints limited the feasibility of pooling prior to the maximal incidence that favored cost savings.
Jan 28, 2023 | Nature Communications
A modular vaccine platform enabled by decoration of bacterial outer membrane vesicles with biotinylated antigens
Researchers unveil AvidVax, a novel platform for designing precise and versatile vaccines. This method leverages engineered bacterial structures to deliver key immune targets, triggering robust immune responses in animal models. AvidVax holds promise for accelerated development of effective vaccines against diverse pathogens.
Jan 01, 2023 | The Lancet Neurology
Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study
A new study delves into the brains of individuals with different Alzheimer's risk factors, comparing the timing and location of protein deposits linked to memory loss. This research could unlock key differences in disease progression and offer valuable insights for future treatments.
Sep 26, 2022 | UCI News
UCI awarded $13.8 million federal contract to profile lipid nanoparticles
Findings will increase understanding of vaccine immune responses and side effects.
Sep 22, 2022 | UCI News
UCI is key member of multi-institutional, $126 million NIH brain mapping project
Campus to receive $10 million over five years for role in Cell Atlas Network
Sep 19, 2022 | UCI News
Precision health perspectives
Daniel Chow discusses how physicians can use artificial intelligence tools to benefit patients
Jul 06, 2022 | UCI School of Medicine
UCI researcher leads study linking ALS to immune and central nervous systems
Findings show promise of bone marrow transplants as novel treatment approach
Jun 07, 2022 | UCI News
UCI wins 5-year, $14M NIH grant to study brain circuits susceptible to aging, Alzheimer’s disease
Findings will advance development of better early diagnostic tools, new treatment strategies
Apr 11, 2022 | UCI School of Medicine
New study from UCI reveals how to rejuvenate the immune system of elderly people and reduce their risk of infectious disease
Results identify reason for why older adults are significantly more susceptible to infectious diseases.