May 11, 2023 | UCI School of Medicine

UCI School of Medicine Recognizes Asian American Native Hawaiian & Pacific Islander Heritage Month

As the only public medical school in Orange County, the UCI School of Medicine celebrates our colleagues who are creating opportunities for themselves and other members of the AANHPI community to hone their leadership skills as they work to expand our mission: Discover. Teach. Heal.

Feb 03, 2023 | PLOS One

Real-world performance of SARS-Cov-2 serology tests in the United States, 2020

Real-world performance of COVID-19 diagnostic tests under Emergency Use Authorization (EUA) must be assessed. We describe overall trends in the performance of serology tests in the context of real-world implementation.

Feb 01, 2023 | Microbiology Spectrum

Beyond Costs: Pragmatic Considerations for Pooling of SARS-CoV-2 Test Samples for Nursing Home Surveillance

Pooling of samples can increase throughput and reduce costs for large-scale SARS-CoV-2 testing when incidence is low. In a cross-sectional study of serial SARS-CoV-2 sampling of staff and residents at three nursing homes, laboratory labor constraints limited the feasibility of pooling prior to the maximal incidence that favored cost savings.

Jan 28, 2023 | Journal of Neuropathology & Experimental Neurology

Neuropathology of microbleeds in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)

CADASIL brains reveal surprising iron deposits. A new study finds increased iron scattered throughout, not just around blood vessels, challenging previous assumptions. This unexpected finding opens doors for further research into iron's role in this rare brain disease.

Jan 28, 2023 | Nature Communications

A modular vaccine platform enabled by decoration of bacterial outer membrane vesicles with biotinylated antigens

Researchers unveil AvidVax, a novel platform for designing precise and versatile vaccines. This method leverages engineered bacterial structures to deliver key immune targets, triggering robust immune responses in animal models. AvidVax holds promise for accelerated development of effective vaccines against diverse pathogens.

Jan 01, 2023 | The Lancet Neurology

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

A new study delves into the brains of individuals with different Alzheimer's risk factors, comparing the timing and location of protein deposits linked to memory loss. This research could unlock key differences in disease progression and offer valuable insights for future treatments.