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Jun 25, 2021 | UCI School of Medicine
Loss of circadian regulation allows for increase in glucose production during lung cancer progression
New study identifies possible therapeutic target to suppress cancer cell growth
Jun 23, 2021 | UCI School of Medicine
New study finds abnormal response to cellular stress is associated with Huntington’s disease
A new University of California, Irvine-led study finds that the persistence of a marker of chronic cellular stress, previously associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), also takes place in the brains of Huntington’s disease (HD) patients.
Jun 22, 2021 | UCI School of Medicine
Study finds most common protein in blood is instrumental in enabling human fertilization and fighting infection
Albumin activates a proton channel leading to human sperm capacitation and sustained release of inflammatory mediators by neutrophils
Jun 18, 2021 | UCI School of Medicine
Study reveals new therapeutic target for C. difficile infection
A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.
Jun 04, 2021 | UCI School of Medicine
World-renowned researcher Vladimir Kefalov joins UCI Departments of Ophthalmology and Physiology & Biophysics
After a nationwide search, Vladimir Kefalov, PhD, has been appointed professor in the Departments of Ophthalmology and Physiology & Biophysics effective June 1, 2021.
Jun 01, 2021
UCI-led study sheds light on mysterious genotype-phenotype associations
New data contributes to knowledge about the molecular mechanisms underlying many human complex traits and diseases
May 13, 2021 | UCI School of Medicine
New study finds low levels of a sugar metabolite associates with disability and neurodegeneration in multiple sclerosis
A new University of California, Irvine-led study finds low serum levels of the sugar N-acetylglucosamine (GlcNAc), is associated with progressive disability and neurodegeneration in multiple sclerosis (MS).
Apr 14, 2021 | UCI School of Medicine
New discovery could lead to therapies for patients with Duchenne muscular dystrophy
A new study, led by the University of California, Irvine (UCI), reveals how chronic inflammation promotes muscle fibrosis, which could inform the development of new therapies for patients suffering from Duchenne muscular dystrophy (DMD), a fatal muscle disease.
Apr 06, 2021 | UCI School of Medicine
UCI awarded 5-year, $4.2M grant to study rare muscle disorder affecting aging Americans
Currently untreatable, sporadic inclusion body myositis (sIBM) causes muscle weakness and severe disability
Apr 01, 2021 | UCI School of Medicine
UCI-led team awarded $2.3 million as part of the California Initiative to Advance Precision Medicine
Precision medicine will be used to study the impacts of adverse and unpredictable experiences on children's neurodevelopment