Radiological Sciences About Us Message from the Chair Outreach Contact Us Education & Training Residency Programs Diagnostic Radiology Residency Integrated Interventional Radiology Residency Independent Interventional Radiology Residency Fellowship Programs Resident & Fellow Resources Research Faculty Labs & Research Centers Divisions Abdominal Imaging Breast Imaging Cardiothoracic Imaging Musculoskeletal Imaging Neuroradiology Imaging Nuclear Medicine and Molecular Imaging Pediatric Imaging Vascular & Interventional Radiology Clinical Expertise Clinical Programs Faculty Histotripsy Home About Campus & Community Resources Communications & Public Relations Office Radiological Sciences: Clinical Expertise > Clinical Programs > Histotripsy Non-Invasive, Targeted Liver Tumor Treatment Histotripsy is a noninvasive medical procedure that uses high-intensity sound waves to destroy liver tumors. Unlike other treatment methods, histotripsy does not require radiologists to make cuts or incisions, use needles or rely on ionizing radiation. The procedure can be performed under general anesthesia and involves ultrasound imaging to locate the targeted tissue and monitor the treatment in real time. How is Histotripsy Performed? Histotripsy involves placing a treatment head, which emits sound waves, inside a soft, flexible membrane containing specially treated water. This membrane is then positioned on a patient’s abdomen and directed at the liver tumor. The sound waves create a bubble cloud from the rapid expansion and collapse of naturally occurring gas bubbles within the tissue, destroying the targeted tissue. What are the Benefits of Histotripsy? Non-invasive The procedure does not require incisions, needles or any other insertions through the skin, which helps reduce the risk of infection, bleeding, long recovery times and other complications. Targeted Histotripsy can be used to precisely target and destroy unwanted tissue, such as tumors, while minimizing damage to surrounding tissue. Single Treatment Most tumors less than 3 cm can be effectively destroyed in a single treatment session. Multiple treatment sessions may be necessary depending on a patient’s clinical condition and treatment plan. Patient Care Please visit our healthcare website for more information on histotripsy, including patient FAQs, and additional benefits and risks associated with the procedure. RADIOLOGY SERVICES