Common Cholesterol Drugs Show Promise Against Chemotherapy-Resistant Pancreatic Cancer

Pancreatic cancer can become harder to treat when tumors stop responding to chemotherapy, leaving patients and families with few options. UC Irvine researchers have identified a weakness that emerges as cancer cells resist a widely used chemotherapeutic, pointing to a possible new use for cholesterol-lowering statins.

Lbachir BenMohamed, PhD, Receives $3.2 Million NIH Grant to Develop Immunotherapy Against Recurrent Ocular Herpes

“Our goal is to develop a safe and durable immunotherapy that can reduce potentially blinding recurrent herpetic disease, limit transmission and ultimately improve the lives of millions of people worldwide,” says Lbachir BenMohamed, PhD.

UC Irvine Receives $4.2 Million NIH Award to Continue All of Us Enrollment and to Study Cardiometabolic Health in Underrepresented Communities

A collaborative project supported by the NIH All of Us Research Program and National Institute on Minority Health and Health Disparities explores genetics, environment and lifestyle factors.

Stopping Chronic Pain Before it Starts

UC Irvine researchers find that after an injury, support cells are temporarily rewired to trigger nerve cells to produce sticky beta-amyloid protein fragments best known for their role in Alzheimer’s disease.

New Data Infrastructure Award to Help Scientific Communities Build Domain-Specific Platforms for Collaborative Data Science and AI

Researchers at UC Irvine, UCLA and the University of Michigan have received nearly $9 million from the U.S. National Science Foundation to establish a new data infrastructure capability that will help scientific communities across the nation use advanced data science and artificial intelligence tools.

Math and Medicine Join Forces to Solve a Cancer Mystery

UC Irvine scientists uncover a key cause of immunotherapy failure – and a path to overcoming it.

Lifesaving Cancer Treatment Without Life-Threatening Side Effects

Researchers at UC Irvine have developed a new framework that could help make CAR T-cell therapy safer.

ProBio's AAV Manufacturing Excellence Powers UC Irvine and GlyTR Therapeutics First‑in‑Class Pan-Cancer CAR‑T Program

UC Irvine researchers and GlyTR Therapeutics have advanced a groundbreaking, first-in-class pan-cancer CAR-T platform with the potential to expand the reach of cell therapy into solid tumors.

Researchers Develop a Potential Blood Test for Diagnosing ALS

UC Irvine researchers are part of an international team developing a new blood test to diagnose ALS and track its progression.

CBD to Alleviate ‘Chemo Brain’ in Cancer Survivors

A new study by UC Irvine researchers suggests that CBD can help treat “brain fog” for people with cancer-therapy-related cognitive impairments (CRCI), addressing an unmet medical need.