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Jan 13, 2025 | Phys.org
Nuclear speckles identified as key hubs for gene expression regulation
UCI researchers, including Yongsheng Shi, PhD, professor in the Department of Microbiology and Molecular Genetics, and first author Yoseop Yoon, PhD, uncover the critical role of nuclear speckles as the major site of pre-mRNA 3' end processing.
Jan 08, 2025 | UC Irvine News
UC Irvine-led team discovers potential new therapeutic targets for Huntington’s disease
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington’s disease and link HD with other neurodegenerative disorders such as amyotrophic lateral sclerosis, frontotemporal lobar dementia and Alzheimer’s disease.
Jan 07, 2025 | Nature
Career Pathways: Part 16
Cholsoon Jang, PhD, assistant professor in the Departments of Biological Chemistry and Medicine, shares how the COVID-19 pandemic impacted his journey to UC Irvine School of Medicine and how curiosity has driven his scientific journey from a very early age.
Jan 06, 2025 | UC Irvine News
New mechanism discovered that triggers immune response in cells with damaged DNA
A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This finding could lead to more effective cancer treatments.
Jan 03, 2025 | The Wall Street Journal
The Mystery of What’s Causing Young People’s Cancer Leads to the Gut
Selma Masri, PhD, associate professor in the Department of Biological Chemistry, shares her research and understanding of the microbiome, contributing to our understanding of the cause of increasing cancer cases among young people.
Oct 31, 2024 | UC Irvine School of Medicine
UC Irvine Researchers Develop Innovative CRISPR-Cas9 Method to Understand Antiviral Defense Response
A UC Irvine research team led by Rémi Buisson have developed a new, unbiased method utilizing CRISPR-Cas9 technology to identify novel regulators of the human antiviral defense response.
Sep 30, 2024 | Graduate Studies
UCI School of Medicine's PhD Orientation 2024
UCI School of Medicine welcomes 36 incoming PhD students for the 2024-2025 academic year.
Meet the Incoming School of Medicine PhD Students
Introducing the newest cohort of 36 PhD students in Biomedical Sciences for this fall. These students will conduct research under the guidance of their advisors in one of our five PhD degree-granting departments: Anatomy & Neurobiology, Biological Chemistry, Experimental Pathology, Microbiology & Molecular Genetics, and Physiology & Biophysics.
Sep 27, 2024 | UC Irvine News
Circadian disruption, gut microbiome changes linked to colorectal cancer progression
Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body’s internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function.
Aug 02, 2024 | UC Irvine School of Medicine
Biological Chemistry Professor Named a 2024 Pew Scholar
Cholsoon Jang, PhD, assistant professor in the Department of Biological Chemistry at UC Irvine School of Medicine, has been named a 2024 Pew Scholar in the Biomedical Sciences.