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Jun 28, 2024 | UCI School of Medicine
UC Irvine researchers investigate muscle cell development in muscular dystrophy
Facioscapulohumeral muscular dystrophy (FHSD) is one of the most common muscular dystrophies, which results in progressive weakening of skeletal muscles. Now, a new study published in Genome Research by UCI School of Medicine researchers utilize cutting-edge single-cell spatial transcriptomics to analyze gene expression in individual nuclei and myocytes of disease and control samples to determine how the disease state develops during human skeletal myocyte differentiation.
Jun 04, 2024 | UCI School of Medicine
UCI researchers awarded a NIAMS T32 grant for PhD training
Kyoko Yokomori, PhD, professor in the Department of Biological Chemistry, Tahseen Mozaffar, MD, professor in the Department of Neurology, and Armando Villalta, PhD, associate professor in the Department of Physiology & Biophysics, were awarded a NIAMS T32 grant titled "MAXIMUS: MAXimizing Training in MUScle Research."
May 28, 2024 | UCI News
UC Irvine study reveals circadian clock can be leveraged to enhance cancer immunotherapy
A multidisciplinary research team at UCI has revealed that the circadian clock can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy, offering new avenues for prevention and treatment.
Apr 09, 2024 | Huntington's Disease News
New genetic database may help in better understanding Huntington’s
Huntington's Disease News covers recent UCI-led research on the first tandem repeat expansions genetic reference maps, a tool to study mutations connected to several human diseases, including Huntington's.
Apr 05, 2024 | UCI News
UC Irvine-led research team builds first tandem repeat expansions genetic reference maps
Tool gives potential to expand insight into diseases, neurological disorders and cancers.
Mar 18, 2024 | UCI News
UC Irvine-led research team discovers role of key enzymes that drive cancer mutations
A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.
Feb 08, 2024 | UCI School of Medicine
UC Irvine team develops innovative MESA liquid biopsy technologies for early disease detection and prognosis
Detecting human cancers through cell-free DNA (cfDNA) in blood is a sensitive and non-invasive option. However, capturing multiple forms of epigenetic information remains a technical and financial challenge.
Dec 07, 2023 | UCI School of Medicine
UC Irvine researchers discover a mechanism that controls the identity of stem cells
Scientists detect the molecular basis of totipotency and its role in embryonic development which could lead to treatment for cancer and neurological disorders.
Nov 06, 2023 | Graduate Studies
UCI School of Medicine's PhD Orientation 2023
UCI School of Medicine welcomes 36 new PhD students for the fall of 2023.
Nov 01, 2023 | UCI School of Medicine
NIH awards $4.4 million to UCI Diabetes Center to study the epigenetic mechanisms for diabetes
Qin Yang, MD, PhD, endocrinologist, director of the UCI Diabetes Center and associate professor in the Departments of Medicine, and Physiology & Biophysics, at the UCI School of Medicine, has received two NIH awards totaling $4.4 million to study the epigenetic mechanisms for diabetes. Wei Li, PhD, professor of bioinformatics in the Department of Biological Chemistry at the UCI School of Medicine, is the co-principal investigator on both awards.