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Jan 01, 2023 | The Lancet Neurology

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

A new study delves into the brains of individuals with different Alzheimer's risk factors, comparing the timing and location of protein deposits linked to memory loss. This research could unlock key differences in disease progression and offer valuable insights for future treatments.
Principal investigators on the project, which is supported by the National Institute of Allergy and Infectious Diseases

Sep 26, 2022 | UC Irvine News

UCI awarded $13.8 million federal contract to profile lipid nanoparticles

Findings will increase understanding of vaccine immune responses and side effects.
UCI research team members that are part of the BRAIN Initiative Cell Atlas Network project

Sep 22, 2022 | UC Irvine News

UCI is key member of multi-institutional, $126 million NIH brain mapping project

Campus to receive $10 million over five years for role in Cell Atlas Network
Dr. Daniel Chow

Sep 19, 2022 | UC Irvine News

Precision health perspectives

Daniel Chow discusses how physicians can use artificial intelligence tools to benefit patients
Albert LaSpada, MD, PhD, distinguished professor of pathology, neurology and biological chemistry

Jul 06, 2022 | UC Irvine School of Medicine

UCI researcher leads study linking ALS to immune and central nervous systems

Findings show promise of bone marrow transplants as novel treatment approach

Xiangmin Xu, Ph.D., UCI Chancellor’s Fellow of anatomy and neurobiology and principal investigator

Jun 07, 2022 | UC Irvine News

UCI wins 5-year, $14M NIH grant to study brain circuits susceptible to aging, Alzheimer’s disease

Findings will advance development of better early diagnostic tools, new treatment strategies
Michael Demetriou, MD, PhD

Apr 11, 2022 | UC Irvine School of Medicine

New study from UCI reveals how to rejuvenate the immune system of elderly people and reduce their risk of infectious disease

Results identify reason for why older adults are significantly more susceptible to infectious diseases.
Farahnaz Rahmatpanah, PhD

Jan 11, 2022 | UC Irvine School of Medicine

UCI-led research team discovers a molecular feature in prostate cancer with prognostic value, distinguishes ancestral differences

Expression signatures may be useful for assessing greatest risk of progression in prostate and other cancers

Dr. Ira Lott and patient in exam room

Oct 22, 2020 | UC Irvine School of Medicine

NIH Awards Over $100 Million to Examine Biomarkers of Alzheimer’s Disease in Adults with Down Syndrome

The Alzheimer’s Biomarkers Consortium – Down Syndrome (ABC-DS), a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health (NIH), to expand research on the biomarkers of Alzheimer’s disease in adults with Down syndrome.
Seyed Ahmad Sajjadi, MD, PhD

Mar 23, 2020 | UC Irvine School of Medicine

UCI researcher receives $3.5 million grant to study older adults diagnosed with dementia

Study will examine hippocampal sclerosis (HS) that often mimics Alzheimer's