Jan 14, 2025 | UCI News

UC Irvine-led study shows crucial role of staffing instability in nursing home ratings

A study led by the University of California, Irvine has revealed the significant impact of staffing instability on nursing home quality across the country, as reflected in the Five-Star Quality Rating System published by the Centers for Medicare & Medicaid Services.

Jan 08, 2025 | UCI News

UC Irvine-led team discovers potential new therapeutic targets for Huntington’s disease

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington’s disease and link HD with other neurodegenerative disorders such as amyotrophic lateral sclerosis, frontotemporal lobar dementia and Alzheimer’s disease.

Jan 07, 2025 | UCI News

UC Irvine-led study challenges traditional risk factors for brain health in the oldest-old

A study led by the University of California, Irvine, has found that cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, are not associated with an increased risk of such harm in individuals 90 and older.

Jan 06, 2025 | UCI News

New mechanism discovered that triggers immune response in cells with damaged DNA

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This finding could lead to more effective cancer treatments.

Dec 03, 2024 | UCI News

UC Irvine-co-led Study Finds DNA Damage is Key Factor in Age-related Macular Degeneration

A research team co-led by the University of California, Irvine has discovered that accumulated DNA damage in the retina is a key contributor to age-related macular degeneration and that targeting specific retinal cell types may lead to treatments that slow or stop progression.