Home Department
Medicine
Sastry Gollapudi, MD
- Asst Adjunct Professor
- Aging
- Apoptosis
- bcl-2-Associated X Protein
- Breast Neoplasms
- Caspases
- CD8-Positive T-Lymphocytes
- fas Receptor
- Immunologic Memory
- Lymphocytes
- Phagocytosis
- Proto-Oncogene Proteins c-bcl-2
- Saccharomyces cerevisiae
- T-Lymphocyte Subsets
- Tumor Necrosis Factor-alpha
- Xylans
- Adaptive Cellular Responses following SARS-CoV-2 Vaccination in Primary Antibody Deficiency Patients. Pathogens. 2024 Jun 18; 13(6). Gupta S, Su H, Agrawal S, Demirdag Y, Tran M, Gollapudi S. PMID: 38921811.
- Phenotypic Analysis of CD4+ Treg, CD8+ Treg, and Breg Cells in Adult Common Variable Immunodeficiency Patients. Int Arch Allergy Immunol. 2019; 180(2):150-158. Yesillik S, Agrawal S, Gollapudi SV, Gupta S. PMID: 31284281.
- Molecular changes associated with increased TNF-a-induced apoptotis in naïve (TN) and central memory (TCM) CD8+ T cells in aged humans. Immun Ageing. 2018; 15:2. Gupta S, Su H, Agrawal S, Gollapudi S. PMID: 29387134.
- FcµR in human B cell subsets in primary selective IgM deficiency, and regulation of FcµR and production of natural IgM antibodies by IGIV. Hum Immunol. 2016 Dec; 77(12):1194-1201. Gupta S, Agrawal S, Gollapudi S, Kubagawa H. PMID: 27751883.
- Reversal of oxidative stress-induced apoptosis in T and B lymphocytes by Coenzyme Q10 (CoQ10). Am J Clin Exp Immunol. 2016; 5(2):41-7. Gollapudi S, Gupta S. PMID: 27168954.
- Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. Exp Gerontol. 2013 Nov; 48(11):1285-92. Agrawal S, Gollapudi S, Gupta S, Agrawal A. PMID: 23988651.
- Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans. Immun Ageing. 2013 Jan 23; 10(1):3. Gupta S, Agrawal S, Gollapudi S. PMID: 23343052.
- Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. Am J Nephrol. 2012; 36(1):50-7. Ichii H, Masuda Y, Hassanzadeh T, Saffarian M, Gollapudi S, Vaziri ND. PMID: 22722756.
- Leptin activates human B cells to secrete TNF-a, IL-6, and IL-10 via JAK2/STAT3 and p38MAPK/ERK1/2 signaling pathway. J Clin Immunol. 2011 Jun; 31(3):472-8. Agrawal S, Gollapudi S, Su H, Gupta S. PMID: 21243519.
- Impaired functions of peripheral blood monocyte subpopulations in aged humans. J Clin Immunol. 2010 Nov; 30(6):806-13. Nyugen J, Agrawal S, Gollapudi S, Gupta S. PMID: 20703784.
- Impaired pneumovax-23-induced monocyte-derived cytokine production in patients with common variable immunodeficiency. J Clin Immunol. 2010 May; 30(3):435-41. Hong R, Agrawal S, Gollapudi S, Gupta S. PMID: 20177958.
- Age-related alterations of gene expression patterns in human CD8+ T cells. Aging Cell. 2010 Feb; 9(1):19-31. Cao JN, Gollapudi S, Sharman EH, Jia Z, Gupta S. PMID: 19878143.
- Effect of end-stage renal disease on B-lymphocyte subpopulations, IL-7, BAFF and BAFF receptor expression. Nephrol Dial Transplant. 2010 Jan; 25(1):205-12. Pahl MV, Gollapudi S, Sepassi L, Gollapudi P, Elahimehr R, Vaziri ND. PMID: 19684120.
- Susceptibility of the human LNCaP prostate cancer cells to the apoptotic effect of marina crystal minerals (MCM) in vitro. Oncol Rep. 2009 Jul; 22(1):155-9. Ghoneum M, Gollapudi S. PMID: 19513518.
- An iron-based beverage, HydroFerrate fluid (MRN-100), alleviates oxidative stress in murine lymphocytes in vitro. Nutr J. 2009 May 02; 8:18. Ghoneum M, Matsuura M, Gollapudi S. PMID: 19409106.
- Differential effect of human herpesvirus 6A on cell division and apoptosis among naive and central and effector memory CD4+ and CD8+ T-cell subsets. J Virol. 2009 Jun; 83(11):5442-50. Gupta S, Agrawal S, Gollapudi S. PMID: 19297473.
- S. cerevisiae induces apoptosis in human metastatic breast cancer cells by altering intracellular Ca2+ and the ratio of Bax and Bcl-2. Int J Oncol. 2008 Sep; 33(3):533-9. Ghoneum M, Matsuura M, Braga M, Gollapudi S. PMID: 18695883.
- Gross thymic extract, Thymax, induces apoptosis in human breast cancer cells in vitro through the mitochondrial pathway. Anticancer Res. 2008 May-Jun; 28(3A):1603-9. Ghoneum M, Seto Y, Sato S, Ghoneum A, Braga M, Gollapudi S. PMID: 18630518.
- MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin. Cancer Detect Prev. 2008; 32(1):1-6. Gollapudi S, Ghoneum M. PMID: 18406070.
- CD95-mediated apoptosis in naïve, central and effector memory subsets of CD4+ and CD8+ T cells in aged humans. Exp Gerontol. 2008 Apr; 43(4):266-74. Gupta S, Gollapudi S. PMID: 18215485.
- Artemisia princeps var orientalis induces apoptosis in human breast cancer MCF-7 cells. Anticancer Res. 2007 Nov-Dec; 27(6B):3891-8. Sarath VJ, So CS, Won YD, Gollapudi S. PMID: 18225547.
- Effector memory CD8+ T cells are resistant to apoptosis. Ann N Y Acad Sci. 2007 Aug; 1109:145-50. Gupta S, Gollapudi S. PMID: 17785300.
- Susceptibility of naïve and subsets of memory T cells to apoptosis via multiple signaling pathways. Autoimmun Rev. 2007 Aug; 6(7):476-81. Gupta S, Gollapudi S. PMID: 17643936.
- Yeast therapy for the treatment of breast cancer: a nude mice model study. In Vivo. 2007 Mar-Apr; 21(2):251-8. Ghoneum M, Wang L, Agrawal S, Gollapudi S. PMID: 17436573.
- Arsenic trioxide induces apoptosis via the mitochondrial pathway by upregulating the expression of Bax and Bim in human B cells. Int J Oncol. 2007 Feb; 30(2):313-8. Baysan A, Yel L, Gollapudi S, Su H, Gupta S. PMID: 17203211.
- Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cells. J Leukoc Biol. 2007 Feb; 81(2):474-82. Agrawal A, Kaushal P, Agrawal S, Gollapudi S, Gupta S. PMID: 17079650.
- Differential sensitivity of naïve and memory subsets of human CD8+ T cells to TNF-alpha-induced apoptosis. J Clin Immunol. 2006 May; 26(3):193-203. Gupta S, Su H, Bi R, Gollapudi S. PMID: 16783459.
- A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis. Immun Ageing. 2006 May 19; 3:5. Gupta S, Agrawal A, Agrawal S, Su H, Gollapudi S. PMID: 16712718.
- Apoptosis of breast cancer MCF-7 cells in vitro is induced specifically by yeast and not by fungal mycelia. Anticancer Res. 2006 May-Jun; 26(3A):2013-22. Ghoneum M, Gollapudi S. PMID: 16827138.
- Thimerosal induces neuronal cell apoptosis by causing cytochrome c and apoptosis-inducing factor release from mitochondria. Int J Mol Med. 2005 Dec; 16(6):971-7. Yel L, Brown LE, Su K, Gollapudi S, Gupta S. PMID: 16273274.
- TNF-alpha-induced apoptosis in human naïve and memory CD8+ T cells in aged humans. Exp Gerontol. 2006 Jan; 41(1):69-77. Gupta S, Gollapudi S. PMID: 16289923.
- Synergistic role of arabinoxylan rice bran (MGN-3/Biobran) in S. cerevisiae-induced apoptosis of monolayer breast cancer MCF-7 cells. Anticancer Res. 2005 Nov-Dec; 25(6B):4187-96. Ghoneum M, Gollapudi S. PMID: 16309215.
- Molecular mechanisms of TNF-alpha-induced apoptosis in naïve and memory T cell subsets. Autoimmun Rev. 2006 Apr; 5(4):264-8. Gupta S, Gollapudi S. PMID: 16697967.
- Life and death of lymphocytes: a role in immunesenescence. Immun Ageing. 2005 Aug 23; 2:12. Gupta S, Su H, Bi R, Agrawal S, Gollapudi S. PMID: 16115325.
- Central memory and effector memory subsets of human CD4(+) and CD8(+) T cells display differential sensitivity to TNF-{alpha}-induced apoptosis. Ann N Y Acad Sci. 2005 Jun; 1050:108-14. Gupta S, Bi R, Gollapudi S. PMID: 16014525.
- Molecular mechanisms of TNF-alpha-induced apoptosis in aging human T cell subsets. Int J Biochem Cell Biol. 2005 May; 37(5):1034-42. Gupta S, Gollapudi S. PMID: 15743676.
- Human squamous cell carcinoma of the tongue and colon undergoes apoptosis upon phagocytosis of Saccharomyces cerevisiae, the baker's yeast, in vitro. Anticancer Res. 2005 Mar-Apr; 25(2A):981-9. Ghoneum M, Hamilton J, Brown J, Gollapudi S. PMID: 15868937.
- Modified arabinoxylan rice bran (MGN-3/Biobran) enhances yeast-induced apoptosis in human breast cancer cells in vitro. Anticancer Res. 2005 Mar-Apr; 25(2A):859-70. Ghoneum M, Gollapudi S. PMID: 15868920.
- Antitumor activity of trovafloxacin in an animal model. In Vivo. 2005 Jan-Feb; 19(1):269-76. Thadepalli H, Salem F, Chuah SK, Gollapudi S. PMID: 15796186.
- Therapeutic efficacy of moxifloxacin, a new quinolone, in the treatment of experimental intra-abdominal abscesses induced by Bacteroides fragilis in mice. Chemotherapy. 2004 Jun; 50(2):76-80. Thadepalli H, Chuah SK, Gollapudi S. PMID: 15211081.
- Induction of apoptosis in breast cancer cells by Saccharomyces cerevisiae, the baker's yeast, in vitro. Anticancer Res. 2004 May-Jun; 24(3a):1455-63. Ghoneum M, Gollapudi S. PMID: 15274310.
- Characterization of naïve, memory and effector CD8+ T cells: effect of age. Exp Gerontol. 2004 Apr; 39(4):545-50. Gupta S, Bi R, Su K, Yel L, Chiplunkar S, Gollapudi S. PMID: 15050289.
- A role of fas-associated death domain (FADD) in increased apoptosis in aged humans. J Clin Immunol. 2004 Jan; 24(1):24-9. Gupta S, Kim C, Yel L, Gollapudi S. PMID: 14997030.
- Phagocytosis of Candida albicans by metastatic and non metastatic human breast cancer cell lines in vitro. Cancer Detect Prev. 2004; 28(1):17-26. Ghoneum M, Gollapudi S. PMID: 15041073.
- Modified arabinoxylan rice bran (MGN-3/Biobran) sensitizes human T cell leukemia cells to death receptor (CD95)-induced apoptosis. Cancer Lett. 2003 Nov 10; 201(1):41-9. Ghoneum M, Gollapudi S. PMID: 14580685.
- Arsenic trioxide induces apoptosis in peripheral blood T lymphocyte subsets by inducing oxidative stress: a role of Bcl-2. Mol Cancer Ther. 2003 Aug; 2(8):711-9. Gupta S, Yel L, Kim D, Kim C, Chiplunkar S, Gollapudi S. PMID: 12939460.
- Effect of age on molecular signaling of TNF-alpha-induced apoptosis in human lymphocytes. Mech Ageing Dev. 2003 Apr; 124(4):503-9. Gupta S, Chiplunkar S, Kim C, Yel L, Gollapudi S. PMID: 12714259.
- Changes in mitochondrial membrane potential and mitochondrial mass occur independent of the activation of caspase-8 and caspase-3 during CD95-mediated apoptosis in peripheral blood T cells. Int J Oncol. 2003 Mar; 22(3):597-600. Gollapudi S, McCormick MJ, Gupta S. PMID: 12579313.
- Molecular basis of rifampicin-induced inhibition of anti-CD95-induced apoptosis of peripheral blood T lymphocytes: the role of CD95 ligand and FLIPs. J Clin Immunol. 2003 Jan; 23(1):11-22. Gollapudi S, Jaidka S, Gupta S. PMID: 12645856.
- Comparison of telithromycin, a new ketolide, with erythromycin and clarithromycin for the treatment of Haemophilus influenzae pneumonia in suckling, middle aged and senescent mice. Int J Antimicrob Agents. 2002 Sep; 20(3):180-5. Thadepalli H, Chuah SK, Iskandar L, Gollapudi S. PMID: 12385696.
- Rifampicin inhibits CD95-mediated apoptosis of Jurkat T cells via glucocorticoid receptors by modifying the expression of molecules regulating apoptosis. J Clin Immunol. 2002 Jan; 22(1):37-47. Yerramasetti R, Gollapudi S, Gupta S. PMID: 11958592.
- Ciprofloxacin inhibits activation of latent human immunodeficiency virus type 1 in chronically infected promonocytic U1 cells. AIDS Res Hum Retroviruses. 1998 Apr 10; 14(6):499-504. Gollapudi S, Kim CH, Roshanravan B, Gupta S. PMID: 9566552.