Jul 21, 2020 | UC Irvine School of Medicine

New discovery reveals brain network mechanism that causes spatial memory impairment in Alzheimer’s disease

Patients with Alzheimer’s disease frequently suffer from spatial memory loss, such as no recognition of where they are, and forgetting where they put their belongings. They often show a wandering symptom, which is also a feature of spatial memory impairment. Until now, the brain network mechanism that causes spatial memory impairment had been unclear

Jul 13, 2020 | UC Irvine School of Medicine

Pickled capers activate proteins important for human brain and heart health

A compound commonly found in pickled capers has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.

Jun 15, 2020

Caution urged for reopening schools to prevent spread of COVID-19 crisis

With fast-approaching preparations required for a new school year with no consensus plan yet in place, a team of clinicians, scientists and educators – including a University of California, Irvine pediatrician – stress the need for caution when re-opening America’s schools and advocate for large-scale viral testing in children, contract tracing and other actions to avoid compounding the COVID-19 crisis.

Jun 12, 2020

UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies

A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

May 12, 2020

Interdisciplinary research team awarded $3.8M to study molecular changes in the brain caused by Alzheimer’s disease

A team of researchers from the University of California, Irvine and San Diego have been awarded $3.8 million by the National Institute on Aging to conduct an epigenomic analysis of neural circuits in the brain. By revealing molecular changes that occur during the course of Alzheimer’s disease (AD), the team hopes to identify new therapeutic targets and molecular biomarkers for early detection and better treatment.

May 11, 2020

Tu Foundation gives $2.5 million to UCI to support COVID-19 patient care, research

A $2.5 million gift from the John and Mary Tu Foundation to the University of California, Irvine is supporting COVID-19-associated patient care at UCI Health and advance clinical and translational research across campus focused on new ways to test for and treat the viral infection.

Apr 22, 2020

New study could lead to therapeutic interventions to treat cocaine addiction

A new study explains how cocaine modifies functions in the brain revealing a potential target for therapies aimed at treating cocaine addiction. The study was published today in Cell Reports.

Apr 17, 2020

DARPA-funded microchip technology optimizes convalescent plasma therapy for COVID-19 patients

A consortium of California scientists from government, academia and business today published an initial manuscript describing a novel approach to prepare convalescent plasma for COVID-19 patients in BioRxiv.

Apr 13, 2020 | UC Irvine School of Medicine

UCI clinical trial targeting retinitis pigmentosa receives $6.6M grant from California Institute for Regenerative Medicine

New grant to support repeat dosing of previously treated patients and ongoing cell manufacturing activities

Apr 08, 2020 | UC Irvine School of Medicine

UCI-led study finds modifiable risk factors could play a role in Alzheimer’s disease

Amyloid is a key feature of Alzheimer’s disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer’s disease, according to a new study published this week. Other, modifiable risk factors, such as the amount of fats in our blood and how efficiently our bodies generate energy could also play important roles.