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Apr 17, 2020
DARPA-funded microchip technology optimizes convalescent plasma therapy for COVID-19 patients
A consortium of California scientists from government, academia and business today published an initial manuscript describing a novel approach to prepare convalescent plasma for COVID-19 patients in BioRxiv.
Apr 13, 2020 | UCI School of Medicine
UCI clinical trial targeting retinitis pigmentosa receives $6.6M grant from California Institute for Regenerative Medicine
New grant to support repeat dosing of previously treated patients and ongoing cell manufacturing activities
Apr 08, 2020 | UCI School of Medicine
UCI-led study finds modifiable risk factors could play a role in Alzheimer’s disease
Amyloid is a key feature of Alzheimer’s disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer’s disease, according to a new study published this week. Other, modifiable risk factors, such as the amount of fats in our blood and how efficiently our bodies generate energy could also play important roles.
Mar 25, 2020 | UCI School of Medicine
New research predicts purified, prescription-strength fish oil could prevent more than 70,000 adverse cardiovascular events nationwide each year
Abstract to be presented at American College of Cardiology/World Congress of Cardiology conference later this month
Mar 23, 2020 | UCI School of Medicine
UCI researcher receives $3.5 million grant to study older adults diagnosed with dementia
Study will examine hippocampal sclerosis (HS) that often mimics Alzheimer's
Mar 19, 2020
New UCI-led study reveals how skin cells prepare to heal wounds
A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds. Results from the study provide a blueprint for future investigation into pathological conditions associated with poor wound healing, such as in diabetic patients.
Mar 06, 2020 | UCI School of Medicine
Using new genomic technology, UCI researchers discover breast cancer cells shift their metabolic strategy in order to metastasize
New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality in breast cancer patients.
Mar 04, 2020 | UCI School of Medicine
Zombie scanning enables researchers to rapidly study peptide-receptor interactions on the cell surface
In the past, biologically-active peptides – small proteins like neurotoxins and hormones that act on cell receptors to alter physiology – were purified from native sources like venoms and then panels of variants were produced in bacteria, or synthesized, to study the structural basis for receptor interaction. A new technique called zombie scanning renders these older processes obsolete.
Feb 27, 2020 | UCI School of Medicine
Skin and non-adhesive cells on the skin’s surface found to play pivotal role in the formation of fingers and toes
Human fingers are sculpted from a primitive pad-like structure during embryonic development. Sometimes, this process goes awry and babies are born with fused fingers or toes. A new study from the University of California, Irvine reveals new factors involved in the congenital malformation called syndactyly.
Feb 27, 2020
Bifunctional nanobodies proven effective at protecting against botulinum neurotoxins including Botox
New study reveals potential for developing novel antibody-based antitoxins against botulinum neurotoxins (BoNTs), including the most commonly used, yet most toxic one, Botox.