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Histological analysis reveals abnormalities in the brains of mice

Sep 12, 2022 | UC Irvine School of Medicine

Surprising discovery by UCI-led team links Piezo1 and cholesterol during brain development

A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.
Group photo of Selma Masri and the three co-authors of the study.

Aug 10, 2022 | UC Irvine School of Medicine

New UCI-led research reveals the circadian clock influences cell growth, metabolism and tumor progression

Study illustrates how both genetic and environmental disruption of the circadian clock can drive colorectal cancer progression
Headshot of Peter Kaiser

Aug 10, 2022 | UC Irvine School of Medicine

New UCI-led study reveals computation-guided approach to suppressing cancer tumor growth

Research holds promise for the development of pharmacological therapies
“The Institute for Precision Health is a skyscraper of sorts at UCI. It will reach epic heights – metaphorically!” says Alpesh Amin.

Jul 29, 2022 | UC Irvine News

Precision health perspectives

Alpesh Amin discusses how utilizing health data can lead to the very best care and chance for good health
stethescope

Jul 18, 2022 | UC Irvine News

What gene changes and blood could tell us about the opioid crisis

UCI scientists win $3.5 million grant for bold addiction research
Bryce Mander, Ph.D., UCI assistant professor of psychiatry & human behavior

Jul 13, 2022 | UC Irvine News

Research reveals how brain inflammation may link Alzheimer’s risk, sleep disturbance

Multisite team included UCI, University of Wisconsin–Madison, Wake Forest University
Albert LaSpada, MD, PhD, distinguished professor of pathology, neurology and biological chemistry

Jul 06, 2022 | UC Irvine School of Medicine

UCI researcher leads study linking ALS to immune and central nervous systems

Findings show promise of bone marrow transplants as novel treatment approach

Image of patient after punch graft treatment.

Jun 26, 2022 | UC Irvine School of Medicine

New UCI-led study reveals characteristics of stable Vitiligo skin disease

Discovery may lead to new treatments to reduce inflammation and promote repigmentation.
Graduate Student Alexa Tierno holds a mouse brain.

Jun 22, 2022 | UC Irvine School of Medicine

UCI neuroscientists create maps of the brain after traumatic brain injury

Findings shed new light on memory and epilepsy. Dr. Robert Hunt and PhD student Alexa Tierno from the Department of Anatomy and Neurobiology were involved in this study.
Xiangmin Xu, Ph.D., UCI Chancellor’s Fellow of anatomy and neurobiology and principal investigator

Jun 07, 2022 | UC Irvine News

UCI wins 5-year, $14M NIH grant to study brain circuits susceptible to aging, Alzheimer’s disease

Findings will advance development of better early diagnostic tools, new treatment strategies