May 08, 2023 | UC Irvine School of Medicine

UCI researchers discover new drugs with potential for treating world’s leading causes of blindness in age-related and inherited retinal diseases

In a University of California, Irvine-led study, researchers have discovered small-molecule drugs with potential clinical utility in the treatment of age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP).

May 03, 2023 | UC Irvine School of Medicine

UC Irvine-led study reveals first clear link between chronic kidney disease and stroke risk

A study led by University of California, Irvine neurology and nephrology experts has revealed the first clear link between chronic kidney disease and increased cerebrovascular disease. It was previously thought that renal disease’s effects on the brain were largely due to hypertension, but researchers discovered that CKD promoted the development of cerebral microhemorrhages independent of blood pressure.

Apr 27, 2023 | UC Irvine School of Medicine

UCI researchers uncover new potential for botulinum neurotoxin E in therapeutic and cosmetic applications

A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).

Apr 03, 2023 | UC Irvine School of Medicine

UCI-led research team discovers mindfulness techniques and online tools ease sickle cell disease pain

Participants experienced a decrease in pain intensity, anxiety and depression after completing the study exercises

Feb 27, 2023 | UC Irvine News

Early-life stress can disrupt maturation of brain’s reward circuits, promoting disorders

UCI discovery offers new therapeutic target for treating mental illness

Feb 22, 2023 | UC Irvine School of Medicine

UCI-led study reveals how lung cells protect themselves against RNA viral infection

A new University of California, Irvine-led study uncovers how a protein, APOBEC3B, could protects cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease. The study was published in Nature Communications.

Feb 09, 2023 | UC Irvine News

UCI to launch pre-health program with support from state of California

Increasing underrepresented students’ access to careers in medicine is the focus of a new interdisciplinary, pre-health professional development program at the University of California, Irvine.

Feb 07, 2023 | UC Irvine News

UCI School of Medicine associate professor awarded 19th Japan Academy Medal

Kei Igarashi, associate professor of anatomy & neurobiology at the University of California, Irvine School of Medicine, has been named one of six scholars to win the 19th Japan Academy Medal.

Jan 17, 2023 | UC Irvine News

UC Irvine, UCLA researchers identify new therapeutic approach to prevent ARDS

A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS. Their study, which appears in iScience, describes the first specific treatment designed to prevent the deadly disease, which can appear in patients with severe lung injury from infections with bacteria and viruses, like pneumonia, flu, respiratory syncytial virus (RSV) and COVID-19.

Dec 21, 2022 | UC Irvine News

UC Irvine-led study links metabolism changes in certain brain cells to Huntington’s disease — Findings show high-dose thiamine and biotin treatments can restore normal processes

A research team led by the University of California, Irvine has linked the mutation that causes Huntington’s disease to developmental deficits in the brain’s oligodendrocyte cells that are caused by changes in metabolism.