Research
Education
Healthcare
Community
About
Oct 22, 2021 | UCI School of Medicine
UCI-led study first to reveal specific molecular mechanism that controls the transition from acute to chronic pain
A new study led by University of California, Irvine researchers is the first to reveal the specific molecular mechanism that controls the transition from acute to chronic pain, and identifies this mechanism as a critical target for disease-modifying medicines.
Sep 20, 2021 | UCI News
Falling Leaves Foundation $30 million lead gift to fund innovative UCI medical research building
Facility to be designed to advance cross-disciplinary teaching, translational research activities
Sep 08, 2021 | UCI School of Medicine
UCI-led research uncovers new mechanism that promotes wound healing in skin
A University of California, Irvine-led study identifies a new molecular pathway that promotes the healing of wounds in the skin. Titled, “GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization,” the study was published today in JCI Insight.
Aug 13, 2021 | UCI School of Medicine
UCI researchers find vital enzyme holds key to the fight against cancer and viral infections; Understanding how to control the enzyme may lead to new treatments against cancers and viral infections
A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A— a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our cells against viral infection—is controlled.
Jul 20, 2021 | UCI School of Medicine
UCI-led study finds unleashing certain T cells may lead to new treatments for multiple sclerosis
In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.
Jun 25, 2021 | UCI School of Medicine
Loss of circadian regulation allows for increase in glucose production during lung cancer progression
New study identifies possible therapeutic target to suppress cancer cell growth
Jun 23, 2021 | UCI School of Medicine
New study finds abnormal response to cellular stress is associated with Huntington’s disease
A new University of California, Irvine-led study finds that the persistence of a marker of chronic cellular stress, previously associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), also takes place in the brains of Huntington’s disease (HD) patients.
Jun 22, 2021 | UCI School of Medicine
Study finds most common protein in blood is instrumental in enabling human fertilization and fighting infection
Albumin activates a proton channel leading to human sperm capacitation and sustained release of inflammatory mediators by neutrophils
Jun 18, 2021 | UCI School of Medicine
Study reveals new therapeutic target for C. difficile infection
A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.
Jun 04, 2021 | UCI School of Medicine
World-renowned researcher Vladimir Kefalov joins UCI Departments of Ophthalmology and Physiology & Biophysics
After a nationwide search, Vladimir Kefalov, PhD, has been appointed professor in the Departments of Ophthalmology and Physiology & Biophysics effective June 1, 2021.