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May 28, 2025 | UC Irvine School of Medicine
UC Irvine Study Finds How Liver, Kidney Work Together to Support NAD⁺ and Healthy Aging
At the center of this discovery is a surprising role for the liver and kidney in working together to support a critical molecule called NAD⁺, which is essential for cellular energy, repair and longevity.
May 27, 2025 | UC Irvine School of Medicine
Study Offers Insights into Cardiovascular Disease by Mapping Organ Interactions
UC Irvine researchers provide the first complete “map” of how organs interact by exchanging metabolites during cardiovascular disease progression, paving the way for organ-specific treatments or diagnostics.
May 20, 2025 | UC Irvine Health Affairs
UC Irvine Celebrates Completion of Falling Leaves Foundation Medical Innovation Building
The building will be one of the largest translational research hubs on the West Coast once it becomes fully operational in the coming months.
May 12, 2025 | KTLA 5
Orange County Woman Opens Up About Living with Fatal, Rare Huntington's Disease
UC Irvine Bren Professor Leslie Thompson, PhD, who’s been researching Huntington’s disease for 35 years, said that while there currently is no cure – there is hope.
Apr 21, 2025 | UC Irvine School of Medicine
New findings reveal why only some cancers respond to ATR inhibitor therapy
UC Irvine researchers gain a better understanding of which types of cancer cells are more sensitive to ATR inhibitor therapy and identify biomarkers that can predict patients’ responses to treatment.
Apr 10, 2025 | UC Irvine School of Medicine
New findings explore how cells fight viruses without harming themselves
A study by UC Irvine researchers examines how our bodies activate defense mechanisms only in the presence of a virus, ensuring that uninfected, healthy cells are not harmed.
Mar 19, 2025 | UC Irvine School of Medicine
UC Irvine School of Medicine Reaches Semifinals of STAT Madness
UC Irvine School of Medicine’s research team has made it through to the Semifinals of STAT Madness, an annual competition by STAT that brings together the best biomedical research from the past year. Research from institutions across the country face off against each other in a bracket-style matchup in which votes determine the winner.
Mar 18, 2025 | UC Irvine School of Medicine
UC Irvine researchers found links that may provide therapeutic targets for neurological diseases
Wei Li, PhD, UC Irvine School of Medicine
Jan 13, 2025 | Phys.org
Nuclear speckles identified as key hubs for gene expression regulation
UCI researchers, including Yongsheng Shi, PhD, professor in the Department of Microbiology and Molecular Genetics, and first author Yoseop Yoon, PhD, uncover the critical role of nuclear speckles as the major site of pre-mRNA 3' end processing.
Jan 08, 2025 | UC Irvine News
UC Irvine-led team discovers potential new therapeutic targets for Huntington’s disease
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington’s disease and link HD with other neurodegenerative disorders such as amyotrophic lateral sclerosis, frontotemporal lobar dementia and Alzheimer’s disease.