Discovery at the Intersection of Down Syndrome & Alzheimer's Disease (video)

Catch a glimpse into the life of UC Irvine researchers as Elizabeth Head, professor of pathology, and Elizabeth Andrews, a Ph.D. candidate in Head’s lab group, explore the intersection of Down syndrome & Alzheimer's disease.

"See how the plaques all form a pattern there?" asks Head, pointing to a screen as she and Andrews examine the brain pathology. "It's really impressive."

Head and Andrews walk you through their recent discovery into how women with Down syndrome might experience faster progression of Alzheimer's disease than men. The finding could reshape when interventions begin and how researchers interpret results in clinical trials — paving the way for more effective therapies for people with Down syndrome and, ultimately, the broader population.

Watch the "From Idea to Impact" video.