Department of Obstetrics and Gynecology Grand Rounds

The Changing Landscape of DNA Damage Repair: New Insights into Ovarian Cancer Management

Lecture by Robert A. Nagourney, MD, Volunteer Associate Professor of Gynecologic Oncology, Department of Obstetrics & Gynecology, UCI School of Medicine

Objectives:

• Provide a historic prospective on the origin of modern chemotherapy
• Explore connections between chemotherapy drug mechanisms and our newer molecular understandings of ovarian carcinogenesis
• Examine future directions in therapy that incorporate DNA damage repair deficiency as a target for treatment