Mar 04, 2020 | UC Irvine School of Medicine

Zombie scanning enables researchers to rapidly study peptide-receptor interactions on the cell surface

In the past, biologically-active peptides – small proteins like neurotoxins and hormones that act on cell receptors to alter physiology – were purified from native sources like venoms and then panels of variants were produced in bacteria, or synthesized, to study the structural basis for receptor interaction. A new technique called zombie scanning renders these older processes obsolete.

Feb 18, 2020

UCI researchers reveal how low oxygen levels in the heart predispose people to life-threatening cardiac arrhythmias

Discovery offers new targets for therapies aimed at preventing sudden death caused by heart attacks