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Schematic summary of new hippocampal circuit connections that are revealed in the new PLOS Biology study

Jan 10, 2022 | UC Irvine School of Medicine

UCI-led team first to discover new neural circuits that regulate spatial learning and memory in the brain’s hippocampal formation

Understanding of novel functional roles can advance research in Alzheimer’s disease, other learning and memory disorders

A conventional tomogram and VPP tomogram

Jan 04, 2022 | UC Irvine School of Medicine

Using cryo-electron tomography, UCI researchers reveal molecular mechanisms underlying mutations within the eye that lead to blindness

Understanding the key structural determinants of a highly specialized membrane in the eye could lead to new treatments, even a cure
Graphic data that describes increased DNA damage in neurons from SCA7 patients

Nov 30, 2021 | UC Irvine School of Medicine

UCI-led study confirms linkage between altered DNA repair and DNA damage in neurodegenerative conditions causing debilitating movement disorders

New research suggests potential therapies to treat spinocerebellar ataxia and its resulting coordination impairments
Description of how two high-throughput screening (HTS) identify the next generation of medications

Nov 16, 2021 | UC Irvine School of Medicine

UCI-led team develops new screening process, could lead to next-generation therapeutics for a broad spectrum of diseases

High-throughput screening provides insight into functional role of key G protein-coupled receptor (GPCR) rhodopsin (Rh)
Picture of UCI's multidisciplinary team of researchers

Nov 15, 2021 | UC Irvine School of Medicine

Multidisciplinary team from UCI publishes new guidance for neuroscience statistical analysis; New guide will lead to more rigorous analysis, reproducibility and richer conclusions

New guide will lead to more rigorous analysis, reproducibility and richer conclusions
Picture of Californian Coast Redwood Forest land

Nov 15, 2021 | UC Irvine School of Medicine

UCI-led study finds single molecule within a specific plant used by Native Americans can treat both pain and diarrhea

UCI-led study finds single molecule within a specific plant used by Native Americans can treat both pain and diarrhea
Ralph and Sue Stern posing for photo outside

Nov 10, 2021 | UC Irvine News

Ralph and Sue Stern gift to support cancer center at new UCI hospital in Irvine; Longtime UCI donors’ latest gift adds to legacy of expanding lifesaving care

Longtime UCI donors’ latest gift adds to legacy of expanding lifesaving care
Microscope image of PIEZO1

Nov 09, 2021 | UC Irvine School of Medicine

UCI researchers reveal critical role of mechanosensor in skin wound healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing.
Xiangmin Xu, PhD, and his colleagues at the UCI Center for Neural Circuit Mapping

Nov 08, 2021 | UC Irvine School of Medicine

UCI Center for Neural Circuit Mapping Investigators receive funding from three federal awards for a total of more than $7M

The University of California, Irvine Center for Neural Circuit Mapping (CNCM) has been awarded three new grants.
Dr. Virginia Kimonis posing for the picture

Nov 04, 2021 | UC Irvine News

UCI and CHOC join new NORD Rare Disease Centers of Excellence Network

Partnership is committed to improving access and care for rare disease patients