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Rapid Correction of Severe Hyponatremia Is Linked With Lower Death Rate
New research findings in JAMA Internal Medicine dispel the dogma that slower hyponatremia correction is better. Faster correction of severe hyponatremia is associated with a lower death rate, according to investigators, including Juan Carlos Ayus, MD, affiliate faculty in the Division of Nephrology, Hypertension and Kidney Transplantation in the Department of Medicine.
UCI School of Medicine Research Insider
January 14, 2025
Nuclear speckles identified as key hubs for gene expression regulation
UCI researchers, including Yongsheng Shi, PhD, professor in the Department of Microbiology and Molecular Genetics, and first author Yoseop Yoon, PhD, uncover the critical role of nuclear speckles as the major site of pre-mRNA 3' end processing.
UC Irvine-led team discovers potential new therapeutic targets for Huntington’s disease
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington’s disease and link HD with other neurodegenerative disorders such as amyotrophic lateral sclerosis, frontotemporal lobar dementia and Alzheimer’s disease.
January 7, 2025
UC Irvine-led study challenges traditional risk factors for brain health in the oldest-old
A study led by the University of California, Irvine, has found that cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, are not associated with an increased risk of such harm in individuals 90 and older.
New mechanism discovered that triggers immune response in cells with damaged DNA
A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This finding could lead to more effective cancer treatments.
The Mystery of What’s Causing Young People’s Cancer Leads to the Gut
Selma Masri, PhD, associate professor in the Department of Biological Chemistry, shares her research and understanding of the microbiome, contributing to our understanding of the cause of increasing cancer cases among young people.
Dean's News & Events Newsletter | 29th Edition
December 2024
December 10, 2024