Clinical Excellence in Nephrology

The Division of Nephrology, Hypertension and Kidney Transplantation at UC Irvine School of Medicine's areas of expertise encompass the comprehensive management of nephrological conditions across various outpatient clinics in Orange, Tustin, Stanton and Irvine.

Doctor conducts ultrasound examination of patient kidney
  • Chronic kidney disease, including disease progression
  • Acute kidney injury
  • Proteinuria and/or hematuria
  • Diabetic and non-diabetic glomerulonephritis
  • Polycystic kidney disease (UC Irvine is a Polycystic Kidney Disease Foundation ADPKD Partner Clinic)
  • Care of pre- and post-transplant patients
  • Fluid, electrolyte and acid-based disorders
  • Home and on-site dialysis treatment
  • Kidney stones 
  • Pregnancy-related kidney disorders, including proteinuria in pregnancy
  • Rare kidney disorders
  • Nutritional management of kidney disease
  • Hypertension treatment (UC Irvine Comprehensive Hypertension Center is certified by the American Heart Association)
  • Chronic dialysis

Our faculty members are dual board-certified in internal medicine and nephrology, specializing in the diagnosis and management of a broad range of kidney diseases. Several faculty members are regularly recognized in professional lists such as Best Doctors in America, America's Top Physicians, Top Doctors, California’s Best Doctors and Orange County Physicians of Excellence.

Kidney Transplant Program

Our kidney transplant program is Orange County’s oldest and largest, offering both living and deceased donor transplants to patients with chronic kidney disease. It is one of the fastest-growing kidney and pancreas transplant programs in California. The program had top Scientific Registry of Transplant Recipients outcomes in the United States in January 2023. The UC Irvine transplant program is partnered with the National Kidney Registry to expand living kidney donation and is a MediCAL-designated National Center of Excellence for Kidney and Pancreas Transplantation.

Transplantation Program Leadership:

Uttam Reddy, MD
Ekamol Tantisattamo, MD
Robert Redfield III, MD, FACS

Explore the program
Kidney ultrasound and analysis of patient kidney condition using kidney ultrasound. Chronic kidney disease and illnesses

The UC Irvine Center for Glomerular Disease is dedicated to providing superior, specialized, and patient-centered treatment for glomerular and rare kidney diseases, including but not limited to IgA nephropathy, focal segmental glomerulosclerosis (FSGS), membranous nephropathy, C3 glomerulopathy and minimal change disease. The center serves as a hub of innovation, research and education, advancing medical knowledge and translating cutting-edge discoveries into improved patient outcomes.

Our comprehensive clinical services include state-of-the-art diagnostics, kidney biopsy and renal pathology, genetic testing and counseling, renal dietitian support and kidney transplant. We collaborate closely with a wide range of specialties at UC Irvine, including but not limited to rheumatology, infectious diseases, reproductive health, urology (including female urology), integrative medicine, gastroenterology, hepatology, hematology and oncology. Our robust research program focuses on glomerular diseases, ranging from translational research to clinical trials. We actively partner with organizations such as the National Kidney Foundation (NKF), NephCure, IgA Nephropathy Foundation and the NEPTUNE Network.

Center Leadership

Ramy Hanna, MD
Yongen Chang, MD, PhD

UC Irvine Comprehensive Hypertension Center

Led by Division of Nephrology & Hypertension faculty member Ekamol Tantisattamo, MD, the Comprehensive Hypertension Center earned this designation from the American Heart Association in 2021. The multidisciplinary team includes a physician, a pharmacist and a dietitian, and manages people with complex or difficult-to-treat hypertension following the latest evidence-based treatment guidelines. UC Irvine is one of only three healthcare facilities in California that has a comprehensive hypertension center. The center was highlighted at the National Kidney Foundation annual meeting in May 2024.

Learn more about our Hypertension Center in this short video produced by Man Kit Michael Siu, MD, MS.

Experience Now

Photo of Douglas Hospital at dusk or dawn.

For information on clinical care, please visit our healthcare website. There, you will find comprehensive information on our services, including details about our center and clinic locations.

Nephrology Services